Manolis Kellis: Biology of Disease | Lex Fridman Podcast #133

Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors:
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EPISODE LINKS:
Manolis Website: http://web.mit.edu/manoli/
Manolis Twitter: https://twitter.com/manoliskellis
Manolis YouTube: https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA
Manolis Wikipedia: https://en.wikipedia.org/wiki/Manolis_Kellis

PODCAST INFO:
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Clips playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOeciFP3CBCIEElOJeitOr41

OUTLINE:
0:00 – Introduction
2:49 – Molecular basis for human disease
26:48 – Deadliest diseases
32:31 – Genetic component of diseases
41:22 – Genetic understanding of disease
57:09 – Unified theory of human disease
1:03:10 – Genome circuitry
1:28:13 – CRISPR
1:39:50 – Mitochondria
1:47:54 – Future of biology research
2:17:30 – The genetic circuitry of disease

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